THE RELATIONSHIP OF PLASMA PROTHROMBIN CONCENTRATiON AND THE DEGRADATION RATE OF SERUM “PROTHROMBIN- CONVERTING FACTOR” DURING DICUMAROL THERAPY
نویسنده
چکیده
on fibrinogen and oxalated plasma revealed that serum obtained from recently coagulated whole blood contains a factor which causes conversion of prothrombin to thrombin.” 2 Since fibrinogen could not be converted to fibrin in any significant degree by addition of fresh serum, and since the rapidity of coagulation of oxalated plasma by the serum factor was proportional to the prothrombin concentration of the plasma, it was assumed that fresh human serum contained a ‘prothrombin-converting factor.” In addition, it was shown that the
منابع مشابه
The relationship of plasma prothrombin concentration and the degradation rate of serum "prothrombin-converting factor" during dicumarol therapy.
on fibrinogen and oxalated plasma revealed that serum obtained from recently coagulated whole blood contains a factor which causes conversion of prothrombin to thrombin.” 2 Since fibrinogen could not be converted to fibrin in any significant degree by addition of fresh serum, and since the rapidity of coagulation of oxalated plasma by the serum factor was proportional to the prothrombin concent...
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Recent studies' have established the presence of a factor ("activator," Coagulase-reacting factor, or CRF) in plasma which is required for the coagulation of blood by staphylocoagulase. Maximum CRF activity resides in the globulin fractions of plasma, and separation from prothrombin is best achieved by repeated Seitz filtration.10 The filtration involves different rates of adsorption of prothro...
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W ITH increasing use of tests of the prothrombin concentration as an aid in the diagnosis of diseases of the liver and as a guide in vitamin K and dicumarol therapy,’6 it is imperative that the determinations be accurate. There are many ways of measuring the prothrombin concentration and each admits of numerous sources of error. Even when the most careful technic is practiced, appreciable error...
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W ITH increasing use of tests of the prothrombin concentration as an aid in the diagnosis of diseases of the liver and as a guide in vitamin K and dicumarol therapy,’6 it is imperative that the determinations be accurate. There are many ways of measuring the prothrombin concentration and each admits of numerous sources of error. Even when the most careful technic is practiced, appreciable error...
متن کاملStandardization of the Quick prothrombin test; with reference to the statistical significance of variations in the prothrombin concentration with use of a stable thromboplastin of high potency.
W ITH increasing use of tests of the prothrombin concentration as an aid in the diagnosis of diseases of the liver and as a guide in vitamin K and dicumarol therapy,’6 it is imperative that the determinations be accurate. There are many ways of measuring the prothrombin concentration and each admits of numerous sources of error. Even when the most careful technic is practiced, appreciable error...
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